Oral or nasal breathing? Real-time effects of switching sampling route onto exhaled VOC concentrations

• Published in: Journal of breath research Vol. 11; no. 2; p. 027101
• Main Authors: Sukul, Pritam, Oertel, Peter, Kamysek, Svend, Trefz, Phillip
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 21.03.2017
• Subjects: Adult; Biomarkers - analysis; Breath tests; Breath Tests - methods; breathing patterns; Carbon Dioxide - analysis; Cardiac Output; Exhalation; Female; Hemodynamics; Humans; Male; Mouth - chemistry; Nasal Cavity - chemistry; oral and nasal breathing; physiological effects; PTR-ToF-MS; respiratory parameters; sampling standardisation; Solubility; Specimen Handling - methods; Tidal Volume; Ventilation; VOCs; Volatile organic compounds; Volatile Organic Compounds - analysis; Young Adult

There is a need for standardisation in sampling and analysis of breath volatile organic compounds (VOCs) in order to minimise ubiquitous confounding effects. Physiological factors may mask concentration changes induced by pathophysiological effects. In humans, unconscious switching of oral and nasal...