Pancreatic neuroendocrine tumors: A review of serum biomarkers, staging, and management

• Published in: World journal of gastroenterology : WJG Vol. 26; no. 19; pp. 2305 - 2322
• Main Authors: Ma, Zu-Yi, Gong, Yuan-Feng, Zhuang, Hong-Kai, Zhou, Zi-Xuan, Huang, Shan-Zhou, Zou, Yi-Ping, Huang, Bo-Wen, Sun, Zhong-Hai, Zhang, Chuan-Zhao, Tang, Yun-Qiang, Hou, Bao-Hua
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Inc 21.05.2020
• Subjects: Ablation Techniques - methods; Antineoplastic Agents - pharmacology; Antineoplastic Agents - therapeutic use; Biomarkers, Tumor - blood; Chemotherapy, Adjuvant - methods; Combined Modality Therapy; Cytoreduction Surgical Procedures; Disease-Free Survival; Humans; Lymph Node Excision; Molecular Targeted Therapy - methods; Neoplasm Grading; Neoplasm Staging; Neuroendocrine Tumors - blood; Neuroendocrine Tumors - diagnosis; Neuroendocrine Tumors - mortality; Neuroendocrine Tumors - therapy; Pancreas - pathology; Pancreas - surgery; Pancreatectomy - methods; Pancreatic Neoplasms - blood; Pancreatic Neoplasms - diagnosis; Pancreatic Neoplasms - mortality; Pancreatic Neoplasms - therapy; Patient Care Team; Prognosis; Progression-Free Survival; Review; Somatostatin - analogs & derivatives; Somatostatin - therapeutic use; Treatment Outcome; Therapy; Management; Serum biomarkers; Grading; Staging; Pancreatic neuroendocrine tumor

Pancreatic neuroendocrine tumors (pNETs) are a heterogeneous group of tumors with complicated treatment options that depend on pathological grading, clinical staging, and presence of symptoms related to hormonal secretion. With regard to diagnosis, remarkable advances have been made: Chromogranin A...