Abnormal right ventricular-pulmonary artery coupling with exercise in heart failure with preserved ejection fraction

• Published in: European heart journal Vol. 37; no. 43; pp. 3293 - 3302
• Main Authors: Borlaug, Barry A., Kane, Garvan C., Melenovsky, Vojtech, Olson, Thomas P.
• Format: Journal Article
• Language: English
• Published: England European Society of Cardiology 14.11.2016
• Subjects: Heart Failure; Heart Ventricles; Humans; Pulmonary Artery; Stroke Volume; Ventricular Dysfunction, Right; Diastolic function; Heart failure; Heart failure with preserved ejection fraction; Exercise; Right ventricular function; Haemodynamics; Pulmonary hypertension

Exercise intolerance is common in people with heart failure and preserved ejection fraction (HFpEF). Right ventricular (RV) dysfunction has been shown at rest in HFpEF but little data are available regarding dynamic RV-pulmonary artery (PA) coupling during exercise. Subjects with HFpEF (n = 50) and...