HLA-DRB103 as a risk factor for microalbuminuria in same duration of type 1 diabetes: a case control study

• Published in: BMC nephrology Vol. 17; no. 37; p. 38
• Main Authors: Ražanskaitė-Virbickienė, Dovilė, Danytė, Evalda, Žalinkevičius, Rimantas
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 31.03.2016; BioMed Central
• Subjects: Adult; Albuminuria - etiology; Albuminuria - genetics; Care and treatment; Case-Control Studies; Complications and side effects; Diabetes Mellitus, Type 1 - complications; Diabetes Mellitus, Type 1 - genetics; Diabetic nephropathies; Female; Genetic aspects; Genetic Predisposition to Disease; Genotype; HLA-DRB1 Chains - genetics; Humans; Male; Risk factors; Type 1 diabetes; Young Adult; Albuminuria; DR3; HLA; AER; DR4; Type 1 diabetes mellitus

Increased urinary albumin excretion rate is the earliest clinical manifestation of diabetic nephropathy. The development of microalbuminuria in patients with type 1 diabetes mellitus (T1D) usually begins 5 to 15 years after the onset of diabetes. The rate of progression of diabetic nephropathy varie...