Observations on the induction of position effect variegation of euchromatic genes in Drosophila melanogaster

• Published in: Genetics (Austin) Vol. 134; no. 1; pp. 231 - 242
• Main Authors: Pokholkova, G V, Makunin, I V, Belyaeva, E S, Zhimulev, I F
• Format: Journal Article
• Language: English
• Published: United States 01.05.1993
• Subjects: Animals; chromatin; chromatine; chromosome; Chromosome Banding; chromosome translocation; chromosomes; Chromosomes - ultrastructure; cromatina; cromosomas; Crosses, Genetic; Drosophila melanogaster; Drosophila melanogaster - genetics; Drosophila melanogaster - ultrastructure; expresion genica; expression des genes; Female; gene; gene expression; gene interaction; Gene Rearrangement; genes; Heterochromatin; heterochromatine; heterocromatina; interaccion de genes; interaction genique; Male; Multigene Family; Mutagenesis; Phenotype; translocacion de cromosomas; translocation chromosomique; Translocation, Genetic; X Chromosome - ultrastructure; Y Chromosome - ultrastructure

In the T(1;2)dor(var7) translocation, the 1A-2B7-8 segment of the X chromosome is brought to the vicinity of 2R-chromosome heterochromatin resulting in position effect variegation of dor, BR-C and more distal genes, as well as compaction of chromatin in this segment. By irradiation of T(1;2)dor(var7...