Innate PI3K p110δ Regulates Th1/Th17 Development and Microbiota-Dependent Colitis - Steinbach, Erin C; Kobayashi, Taku; Russo, Steven M; Sheikh, Shehzad Z; Gipson, Gregory R; Kennedy, Samantha T; Uno, Jennifer K; Mishima, Yoshiyuki; Borst, Luke B; Liu, Bo; Herfarth, Hans; Ting, Jenny P Y; et al. (The Journal of immunology (1950), 2014)
Keywords: Animals; Antigen-Presenting Cells - immunology; Antigen-Presenting Cells - metabolism; Class Ia Phosphatidylinositol 3-Kinase - genetics; Class Ia Phosphatidylinositol 3-Kinase - metabolism; Colitis - genetics; Colitis - immunology; Colitis - metabolism; Colitis - microbiology; Colitis - pathology; Cytokines - biosynthesis; Disease Models, Animal; Gene Expression Regulation; Immunity, Innate - genetics; Interleukin-10 - biosynthesis; Intestinal Mucosa - immunology; Intestinal Mucosa - metabolism; Intestinal Mucosa - microbiology; Intestinal Mucosa - pathology; Macrophages - immunology; Macrophages - metabolism; Male; Mice; Mice, Knockout; Microbiota; Th1 Cells - immunology; Th1 Cells - metabolism; Th17 Cells - immunology; Th17 Cells - metabolism; TOR Serine-Threonine Kinases - metabolism