Assessment and diagnostic relevance of novel serum biomarkers for early decision of ST-elevation myocardial infarction

• Published in: Oncotarget Vol. 6; no. 15; pp. 12970 - 12983
• Main Authors: Park, Hun-Jun, Noh, Ji Heon, Eun, Jung Woo, Koh, Yoon-Seok, Seo, Suk Min, Park, Won Sang, Lee, Jung Young, Chang, Kiyuk, Seung, Ki Bae, Kim, Pum-Joon, Nam, Suk Woo
• Format: Journal Article
• Language: English
• Published: United States Impact Journals LLC 30.05.2015
• Subjects: Acute Coronary Syndrome - blood; Acute Coronary Syndrome - genetics; Acute Coronary Syndrome - physiopathology; Acute Coronary Syndrome - surgery; Biomarkers - blood; Case-Control Studies; Early Diagnosis; Female; Humans; Male; Middle Aged; Myocardial Infarction - blood; Myocardial Infarction - genetics; Myocardial Infarction - physiopathology; Percutaneous Coronary Intervention; Research Paper: Pathology; RNA - blood; RNA - genetics; Transcriptome; Pathology Section; molecular signature; peripheral blood transcriptome; ST-segment-elevation myocardial infarction; diagnostic biomarkers

Blood transcriptome reflects the status of diseases, and characteristic molecular signature provides a novel window on gene expression preceding acute coronary events. We aim to determine blood transcriptome-based molecular signature of acute coronary syndrome (ACS), and to identify novel serum biom...