Correlation between clinical symptoms and striatal DAT uptake in patients with DLB

• Published in: Annals of nuclear medicine Vol. 31; no. 5; pp. 390 - 398
• Main Authors: Shimizu, Soichiro, Hirose, Disuke, Namioka, Nayuta, Kanetaka, Hidekazu, Hirao, Kentaro, Hatanaka, Hirokuni, Takenoshita, Naoto, Kaneko, Yoshitsugu, Ogawa, Yusuke, Umahara, Takahiko, Sakurai, Hirofumi, Hanyu, Haruo
• Format: Journal Article
• Language: English
• Published: Tokyo Springer Japan 01.06.2017; Springer Nature B.V
• Subjects: Aged, 80 and over; Alzheimer's disease; Basal ganglia; Biological Transport; Brain diseases; Central nervous system diseases; Cognition; Cognitive ability; Correlation; Dementia disorders; Dopamine; Dopamine transporter; Female; Fluctuations; Hallucinations; Humans; Imaging; Lewy bodies; Lewy Body Disease - diagnostic imaging; Lewy Body Disease - metabolism; Lewy Body Disease - physiopathology; Male; Medicine; Medicine & Public Health; Movement disorders; Neostriatum; Neostriatum - metabolism; Neurodegenerative diseases; Nuclear Medicine; Original Article; Patients; Photon emission; Putamen; Radiology; Regional analysis; REM sleep; Single photon emission computed tomography; Sleep; Sleep disorders; Tomography; Tomography, Emission-Computed, Single-Photon; Tropanes; Visual perception; Parkinsonism; I-FP-CIT; DAT scan; Alzheimer’s disease; Dementia with Lewy bodies; 123I-FP-CIT

Objective It is widely known that there is low striatal 123 I-FP-CIT dopamine transporter-single photon emission tomography (DAT-SPECT) uptake in patients with dementia with Lewy bodies (DLB). We assessed the correlation between symptom and regional low DAT uptake in the striatum. Methods Patients w...