Nasal vaccines for pertussis

• Published in: Current opinion in immunology Vol. 84; p. 102355
• Main Authors: Schmitt, Pauline, Borkner, Lisa, Jazayeri, Seyed Davoud, McCarthy, Karen N, Mills, Kingston HG
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.10.2023

Whooping cough, caused by Bordetella pertussis, is still a major cause of morbidity and mortality worldwide. Current acellular pertussis (aP) vaccines induce potent circulating IgG and prevent severe disease in children/adults and in infants born to vaccinated mothers. However, they do not prevent n...