The role of damage associated molecular pattern molecules (DAMPs) and permeability of the blood-brain barrier in depression and neuroinflammation

• Published in: Journal of neuroimmunology Vol. 371; p. 577951
• Main Authors: Serna-Rodríguez, María Fernanda, Bernal-Vega, Sofía, de la Barquera, José Alfonso Ontiveros-Sánchez, Camacho-Morales, Alberto, Pérez-Maya, Antonio Alí
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.10.2022
• Subjects: Blood-brain barrier; Cytokines; DAMPs; Depression; Neuroinflammation; Depression; Neuroinflammation; Blood-brain barrier; Cytokines; DAMPs

Depression is a heterogeneous mental disorder characterized by feelings of sadness and loss of interest that render the subject unable to handle basic daily activities such as sleeping, eating, or working. Neurobiological traits leading to depression include genetic background, early life abuse, lif...