Irradiation of Skin with Visible Light Induces Reactive Oxygen Species and Matrix-Degrading Enzymes

• Published in: Journal of investigative dermatology Vol. 132; no. 7; pp. 1901 - 1907
• Main Authors: Liebel, Frank, Kaur, Simarna, Ruvolo, Eduardo, Kollias, Nikiforos, Southall, Michael D.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.07.2012; Nature Publishing Group; Elsevier Limited
• Subjects: Antioxidants - pharmacology; Biological and medical sciences; Cells, Cultured; Cytokines - biosynthesis; Dermatology; Extracellular Signal-Regulated MAP Kinases - physiology; Humans; Light; Luminescent Measurements; Matrix Metalloproteinases - biosynthesis; Medical sciences; Pyrimidine Dimers - biosynthesis; Reactive Oxygen Species - metabolism; Receptor, Epidermal Growth Factor - physiology; Signal Transduction - radiation effects; Skin - metabolism; Skin - radiation effects; Ultraviolet Rays; Oxygen; Skin; Dermatology; Free radical

Daily skin exposure to solar radiation causes cells to produce reactive oxygen species (ROS), which are a primary factor in skin damage. Although the contribution of the UV component to skin damage has been established, few studies have examined the effects of non-UV solar radiation on skin physiolo...