Comprehensive Characterization of Islet Remodeling in Development and in Diabetes Using Mass Cytometry - Toledo, Maria Pilar; Xie, Gengqiang; Wang, Yue J (Endocrinology (Philadelphia), 2024)
Keywords: Adolescent; Adult; Age; Aged; B cells; Beta cells; Cellular structure; Child; Child, Preschool; Cytometry; Data analysis; Development and progression; Developmental plasticity; Diabetes; Diabetes mellitus (insulin dependent); Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 1 - metabolism; Diabetes Mellitus, Type 1 - pathology; Diabetes Mellitus, Type 2 - metabolism; Diabetes Mellitus, Type 2 - pathology; Female; Flow Cytometry - methods; Heterogeneity; Humans; Infant; Insulin-Secreting Cells - cytology; Insulin-Secreting Cells - metabolism; Insulin-Secreting Cells - pathology; Insulin-Secreting Cells - physiology; Islet cells; Islets of Langerhans - metabolism; Islets of Langerhans - pathology; Male; Middle Aged; Pancreas; Pathogenesis; Proteins; Single-Cell Analysis - methods; Structural analysis; Structure-function relationships; Type 2 diabetes; Young Adult; islet remodeling; development; mass cytometry; CyTOF; diabetes