Updosing nonsedating antihistamines in patients with chronic spontaneous urticaria: a systematic review and meta-analysis

• Published in: British journal of dermatology (1951) Vol. 175; no. 6; pp. 1153 - 1165
• Main Authors: Guillén-Aguinaga, S., Jáuregui Presa, I., Aguinaga-Ontoso, E., Guillén-Grima, F., Ferrer, M.
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.12.2016
• Subjects: Chronic Disease; Clinical Trials, Phase II as Topic; Double-Blind Method; Drug Administration Schedule; Histamine H1 Antagonists, Non-Sedating - administration & dosage; Humans; Pruritus - drug therapy; Randomized Controlled Trials as Topic; Treatment Outcome; Urticaria - drug therapy

Summary There is a lack of large, randomized, double‐blind studies that address antihistamine updosing for chronic spontaneous urticaria (CSU). The objective of this systematic review is to explore and analyse available data to provide clinical evidence for the efficacy of antihistamine updosing. We...