NF-κB Activation and Severity of Gastritis in Helicobacter pylori-Infected Children and Adults

• Published in: Helicobacter (Cambridge, Mass.) Vol. 19; no. 3; pp. 157 - 167
• Main Authors: Bontems, Patrick, Aksoy, Ezra, Burette, Alain, Segers, Valérie, Deprez, Carine, Mascart, Françoise, Cadranel, Samy
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.06.2014
• Subjects: Adolescent; Adult; Age Factors; Biopsy; Child; Child, Preschool; children; Female; gastritis; Gastritis - pathology; gastroduodenal ulcer; Helicobacter Infections - complications; Helicobacter Infections - pathology; Helicobacter pylori; Humans; Immunohistochemistry; Infant; Male; NF-kappa B - analysis; NF-κB activation; Peptic Ulcer - epidemiology; Peptic Ulcer - pathology; Prevalence; Severity of Illness Index; NF-κB activation; gastroduodenal ulcer; Helicobacter pylori; children; gastritis

Background In contrast to adults, Helicobacter pylori gastritis in children is reported as milder and ulcer disease as uncommon, but unequivocal data are lacking. Objectives To compare the frequency of gastro‐duodenal ulcers in children and adults as well as the proportion of Helicobacter pylori inf...