Acute toxicological evaluation of bone-targeted parathyroid hormone-related peptide (PTHrP) antagonist to inhibit breast cancer metastases to bone - Ponnapakkam, Tulasi; Anbalagan, Muralidharan; Stratford, Robert E.; Zou, Binghao; Blair, Robert; Rowan, Brian G.; Gensure, Robert (Toxicology reports, 2025)
Keywords: Bone metastases; Breast cancer; Collagen Binding Domain; Drug development; Parathyroid Hormone; PTHrP antagonist; Targeted therapy; Toxicity; AST; CBD; TBS; IHC; PTH; Targeted therapy; Toxicity; PTHrP antagonist; ALT; Breast cancer; Crea; cAMP; EDTA; NOEL; PTHrP; Parathyroid Hormone; Drug development; IV; VC; Bone metastases; AUC; SC; NOAEL; Collagen Binding Domain