Impact of local anesthesia on ciliary dyskinesia diagnosis by digital high‐speed videomicroscopy

• Published in: Pediatric pulmonology Vol. 60; no. 1; pp. e27323 - n/a
• Main Authors: Benchimol, Lionel, Bricmont, Noemie, Bonhiver, Romane, Hans, Grégory A., Lefebvre, Philippe, Kempeneers, Celine, Poirrier, Anne‐Lise
• Format: Journal Article Web Resource
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.01.2025; John Wiley & Sons
• Subjects: Administration, Intranasal; Adolescent; Adult; Anesthesia, Local - methods; Anesthetics, Local - administration & dosage; Child; Cilia - drug effects; Cilia - physiology; ciliary beat frequency; ciliary beat pattern; Ciliary Motility Disorders - diagnosis; diagnostic; digital high-speed videomicrocopy; Dyskinesia; Female; Human health sciences; Humans; Kartagener Syndrome - diagnosis; Lidocaine - administration & dosage; local anaesthesia; Local anesthesia; Male; Medical diagnosis; Microscopy, Video - methods; Nasal Mucosa - drug effects; Oto-rhino-laryngologie; Otolaryngology; primary ciliary dyskinesia; Prospective Studies; Sciences de la santé humaine; Single-Blind Method; Young Adult; digital high‐speed videomicrocopy; diagnostic; local anaesthesia; ciliary beat pattern; primary ciliary dyskinesia; ciliary beat frequency

Summary This prospective study investigates the impact of local anesthesia on ciliary function in nasal epithelium. The primary objective was to assess whether lidocaine 2% and naphazoline 0.5% nasal spray alter ciliary beat frequency and pattern in subjects undergoing nasal brushing, aiming to enha...