Efficacy of Temozolomide Therapy in Patients With Aggressive Pituitary Adenomas and Carcinomas—A German Survey

• Published in: The journal of clinical endocrinology and metabolism Vol. 105; no. 3; pp. e660 - e675
• Main Authors: Elbelt, Ulf, Schlaffer, Sven M, Buchfelder, Michael, Knappe, Ulrich J, Vila, Greisa, Micko, Alexander, Deutschbein, Timo, Unger, Nicole, Lammert, Alexander, Topuzoglu-Müller, Tengü, Bojunga, Jörg, Droste, Michael, Johanssen, Sarah, Kolenda, Herbert, Ritzel, Katrin, Buslei, Rolf, Strasburger, Christian J, Petersenn, Stephan, Honegger, Jürgen
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 01.03.2020; Copyright Oxford University Press
• Subjects: Brain cancer; Brain tumors; Cancer; Carcinoma; Diagnosis; Patients; Pituitary; Pituitary gland; Survival; Temozolomide; Tumors; temozolomide; pituitary carcinoma; aggressive pituitary tumor; progression-free survival; response rate

Abstract Context Despite growing evidence that temozolomide (TMZ) therapy is effective for the treatment of aggressive pituitary tumors (APTs) or carcinomas (PCs), individual therapy decisions remain challenging. Objective We therefore aimed to report on clinical characteristics leading to initiatio...