The experimental design approach to eluotropic strength of 20 solvents in thin-layer chromatography on silica gel

• Published in: Journal of Chromatography A Vol. 1483; pp. 138 - 141
• Main Authors: Komsta, Łukasz, Stępkowska, Barbara, Skibiński, Robert
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 03.02.2017
• Subjects: Chemical Phenomena; Chromatography, Thin Layer - methods; confidence interval; Confidence Intervals; Eluotropic strength; experimental design; Hexanes - chemistry; Linear Models; Mixture design; principal component analysis; regression analysis; Research Design; screening; Silica gel; Silica Gel - chemistry; solvents; Solvents - chemistry; Thin-layer chromatography; uncertainty; variance; Thin-layer chromatography; Silica gel; Mixture design; Eluotropic strength

•Experimental indices of eluotropic strength of 20 solvents were obtained.•The proper experimental design allowed to estimate each solvent as independent factor.•The uncertainty of estimation was studied by additional bootstrapping.•The strength measures have large cognitive value as theoretical RM...