Molecular recognition of a lipophilic guanosine derivative in Langmuir films at the air-water interface

• Published in: Biochimica et biophysica acta. General subjects Vol. 1861; no. 5; pp. 1463 - 1470
• Main Authors: Čoga, Lucija, Spindler, Lea, Masiero, Stefano, Drevenšek-Olenik, Irena
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2017
• Subjects: Air; Air Pressure; Deoxyadenosines - chemistry; deoxycytidine; Deoxycytidine - analogs & derivatives; Deoxycytidine - chemistry; Deoxyguanosine - chemistry; guanosine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Intermolecular recognition; Langmuir monolayer; Lipids - chemistry; Liponucleoside; microscopy; Models, Chemical; Surface Properties; Thymidine - analogs & derivatives; Thymidine - chemistry; Water - chemistry; Liponucleoside; Intermolecular recognition; Langmuir monolayer

Molecular recognition of a lipophilic deoxyguanosine derivative at the air-water interface was investigated by film balance experiments and Brewster Angle Microscopy. Results showed that guanosine, despite strong tendency towards self-assembly, interacts with both complementary and noncomplementary...