A versatile microfluidic platform for the study of cellular interactions between endothelial cells and neutrophils

• Published in: Biochimica et biophysica acta. General subjects Vol. 1861; no. 5; pp. 1122 - 1130
• Main Authors: Wu, Xiaojie, Newbold, Molly A., Gao, Zhe, Haynes, Christy L.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2017
• Subjects: Angiogenesis; cardiovascular diseases; Cell Communication - physiology; cell movement; Cell Movement - physiology; Cells, Cultured; Chemokine; chemokines; Chemokines - metabolism; drugs; endothelial cells; Endothelial Cells - metabolism; Endothelial Cells - physiology; Endothelium, Vascular - metabolism; Endothelium, Vascular - physiology; gels; growth and development; Humans; immune response; in vitro studies; Microfluidic; Microfluidics - methods; Migration; neoplasms; Neutrophil; Neutrophil Infiltration - physiology; neutrophils; Neutrophils - metabolism; Neutrophils - physiology; pathogenesis; Receptor expression; Vascular Endothelial Growth Factor A - metabolism; vascular endothelial growth factors; Chemokine; Angiogenesis; Neutrophil; Migration; Receptor expression; Microfluidic

Endothelial migration is a critical physiological process during vascular angiogenesis, growth and development, as well as in various disease conditions, such as cancer and cardiovascular diseases. Neutrophil migration, known as the important characteristic of immune responses, is also recognized as...