Quantification of Nimesulide in Human Plasma by High-Performance Liquid Chromatography with Ultraviolet Detector (HPLC-UV): Application to Pharmacokinetic Studies in 28 Healthy Korean Subjects - Kim, Mi-Sun; Park, Yoo-Sin; Kim, Shin-Hee; Kim, Sang-Yeon; Lee, Min-Ho; Kim, Youn-Hee; Kim, Do-Wan; Yang, Seok-Chul; Kang, Ju-Seop (Journal of chromatographic science, 2012)
Keywords: Acidification; Administration, Oral; Adult; Analysis; Anti-Inflammatory Agents, Non-Steroidal - administration & dosage; Anti-Inflammatory Agents, Non-Steroidal - blood; Area Under Curve; Asian Continental Ancestry Group; Biological and medical sciences; Blood; Chromatography, High Pressure Liquid - economics; Chromatography, High Pressure Liquid - methods; COX-2 inhibitors; Cyclooxygenase Inhibitors - administration & dosage; Cyclooxygenase Inhibitors - blood; Dosage; Drugs; Ethers; General pharmacology; Humans; Liquid chromatography; Male; Medical sciences; Pharmacology. Drug treatments; Populations; Sensitivity and Specificity; Sulfonamides - administration & dosage; Sulfonamides - blood; Young Adult; Asia; Korea; Human; Validation; Prostaglandin-endoperoxide synthase; Biological fluid; Chemical analysis; Healthy subject; Enzyme; Liquid liquid extraction; Oral administration; Enzyme inhibitor; HPLC chromatography; Solvent extraction; Blood; Blood plasma; Non steroidal antiinflammatory agent; Analgesic; Ultraviolet detector; Sample preparation; Antipyretic; Oxidoreductases; Nimesulide; Pharmacokinetics; Quantitative analysis