Fatty acid synthase 2 knockdown alters the energy allocation strategy between immunity and reproduction during infection by Micrococcus luteus in Locusta migratoria

• Published in: Pesticide biochemistry and physiology Vol. 205; p. 106127
• Main Authors: Ma, Tingting, Tang, Ya, Jin, Yi, Xu, Jiaying, Zhao, Huazhang, Zhou, Min, Tang, Bin, Wang, Shigui
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2024
• Subjects: Animals; atrophy; bacterial infections; Energy; Energy Metabolism; fat body; Fat Body - metabolism; Fatty acid synthase 2; Fatty Acid Synthases - genetics; Fatty Acid Synthases - metabolism; fatty-acid synthase; fecundity; Female; females; Fertility; Gene Knockdown Techniques; genes; glucose; glycogen; immune response; Immunity; Insect Proteins - genetics; Insect Proteins - metabolism; insects; Locusta migratoria; Locusta migratoria - genetics; Locusta migratoria - immunology; Locusta migratoria - microbiology; lysozyme; Micrococcus luteus; Micrococcus luteus - physiology; monophenol monooxygenase; oviposition; pesticides; Reproduction; RNA Interference; triacylglycerols; vitellogenin; Reproduction; Locusta migratoria; Fatty acid synthase 2; Energy; Immunity

Immunity and reproduction are vital functions for the survival and population maintenance of female insects. However, owing to limited resources, these two functions cannot be fulfilled simultaneously, resulting in an energy tradeoff between them. Notably, the mechanisms underlying this immune-repro...