Extracellular matrix dynamics and functions in the social amoeba Dictyostelium: A critical review

• Published in: Biochimica et biophysica acta. General subjects Vol. 1861; no. 1; pp. 2971 - 2980
• Main Authors: Huber, Robert J., O'Day, Danton H.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2017
• Subjects: cell differentiation; Cell motility; cell movement; collagen; Development; Dictyostelium - cytology; Dictyostelium - growth & development; Dictyostelium - metabolism; Dictyostelium discoideum; Disease; EGF-like repeats; Extracellular matrix; Extracellular Matrix - metabolism; Extracellular Matrix Proteins - metabolism; homeostasis; human diseases; Humans; mammals; Matricellular; morphogenesis; neoplasms; proteoglycans; proteolysis; Protozoan Proteins - metabolism; Signal Transduction; CaMBP; SPARC; vWF; EGFL; cAMP; CaMBD; CaM; EGFR; TipD; Dictyostelium discoideum; EGF-like repeats; CaBP; SDF; Development; Extracellular matrix; Matricellular; GRASP; Psa; DIF; AD; Tenascin C; EGF; Cad; Psi; ER; Sib; ECM; Pst; TSP; Cell motility; CV; PD; ALC; HD; AcbA; Tgr

The extracellular matrix (ECM) is a dynamic complex of glycoproteins, proteoglycans, carbohydrates, and collagen that serves as an interface between mammalian cells and their extracellular environment. Essential for normal cellular homeostasis, physiology, and events that occur during development, i...