Sex Modulates the Pathological Aging Effect on Caudate Functional Connectivity in Mild Cognitive Impairment

• Published in: Frontiers in psychiatry Vol. 13; p. 804168
• Main Authors: Yang, Zhengshi, Caldwell, Jessica Z. K., Cummings, Jeffrey L., Ritter, Aaron, Kinney, Jefferson W., Cordes, Dietmar
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 05.04.2022
• Subjects: aging effect; Alzheimer's Disease; caudate; functional connectivity; mild cognitive impairment; Psychiatry; sex difference; mild cognitive impairment; functional connectivity; caudate; aging effect; sex difference; Alzheimer's Disease

To assess the pathological aging effect on caudate functional connectivity among mild cognitive impairment (MCI) participants and examine whether and how sex and amyloid contribute to this process. Two hundred and seventy-seven functional magnetic resonance imaging (fMRI) sessions from 163 cognitive...