Spread of OXA-23-producing Acinetobacter baumannii ST2 and ST246 in a hospital in Japan

• Published in: Journal of medical microbiology Vol. 64; no. 7; pp. 739 - 744
• Main Authors: Kubo, Yumi, Komatsu, Masaru, Tanimoto, Emi, Sugimoto, Keiichi, Tanaka, Satoru, Migita, Shiho, Kondo, Yoko, Yano, Sawa, Maehara, Kuniho, Murata, Ryoko, Nakamura, Akihiro, Fujita, Toshikazu, Kawata, Yoichi
• Format: Journal Article
• Language: English
• Published: England 01.07.2015
• Subjects: Acinetobacter baumannii - drug effects; Acinetobacter baumannii - genetics; Acinetobacter baumannii - isolation & purification; Acinetobacter Infections - drug therapy; Acinetobacter Infections - epidemiology; Anti-Bacterial Agents - therapeutic use; beta-Lactamases - biosynthesis; beta-Lactamases - genetics; Cross Infection - microbiology; Drug Resistance, Multiple, Bacterial - genetics; Hospitals; Humans; Imipenem - therapeutic use; Japan - epidemiology; Meropenem; Microbial Sensitivity Tests; Multilocus Sequence Typing; Thienamycins - therapeutic use

A total of 1085 strains of Acinetobacter sp. obtained from 280 medical institutions in the Chugoku and Shikoku areas of Japan were investigated between 2011 and 2013. Among these strains, 20 (1.84 %) showing meropenem or imipenem resistance with a MIC of >4 μg ml- 1 were detected. Of these 20 str...