Gene network analysis of oxaliplatin-resistant colorectal cancer to target a crucial gene using chitosan/hyaluronic acid/protamine polyplexes containing CRISPR-Cas9 - Shirani-Bidabadi, Shiva; Mirian, Mina; Varshosaz, Jaleh; Tavazohi, Nazita; Sadeghi, Hamid Mir Mohammad; Shariati, Laleh (Biochimica et biophysica acta. General subjects, 2023)
Keywords: Chitosan; Colorectal cancer; colorectal neoplasms; Colorectal Neoplasms - drug therapy; Colorectal Neoplasms - genetics; CRISPR-Cas systems; CRISPR-Cas Systems - genetics; CRISPR/Cas9; DNA repair; Drug resistance; excision; fluorouracil; Gene Regulatory Networks; genes; Humans; Hyaluronic Acid; Oxaliplatin; Oxaliplatin - pharmacology; Oxaliplatin - therapeutic use; particle size; plasmids; Polyplex; Protamines - genetics; Protamines - therapeutic use; sulfates; toxicity; transfection; zeta potential; Polyplex; Oxaliplatin; CRISPR/Cas9; Drug resistance; Colorectal cancer