Exercise training versus diet-induced weight-loss on metabolic risk factors and inflammatory markers in obese subjects: a 12-week randomized intervention study

• Published in: American journal of physiology: endocrinology and metabolism Vol. 298; no. 4; pp. E824 - E831
• Main Authors: Christiansen, Tore, Paulsen, Søren K., Bruun, Jens M., Pedersen, Steen B., Richelsen, Bjørn
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.04.2010
• Subjects: Adipose tissue; Adipose Tissue - metabolism; Adolescent; Adult; Anaerobic Threshold - physiology; Biomarkers; Biomarkers - analysis; Biomarkers - metabolism; Blood Glucose - metabolism; Blood Pressure - physiology; Blood Proteins - analysis; Body Weight - physiology; Cytokines; Diet; Diet, Reducing; Exercise; Exercise - physiology; Female; Gene expression; Gene Expression - physiology; Humans; Inflammation - metabolism; Insulin - blood; Lipids - blood; Male; Metabolism; Middle Aged; Muscle, Skeletal - metabolism; Musculoskeletal system; Obesity; Obesity - diet therapy; Obesity - metabolism; Obesity - therapy; Physical Education and Training; Physical training; Risk Factors; Weight control; Weight Loss - physiology; Young Adult

The purpose of this study was to investigate the effect of exercise training and diet-induced weight loss alone or in combination on inflammatory markers in circulation, in adipose tissue (AT) and in skeletal muscle (SM) in obese subjects. Seventy-nine obese subjects were randomized into a 12-wk int...