De novo DNA methyltransferase DNMT3A: Regulation of oligomeric state and mechanism of action in response to pH changes - Holz-Schietinger, Celeste; Reich, Norbert O. (Biochimica et biophysica acta, 2015)
Keywords: Cancer; DNA; DNA (Cytosine-5-)-Methyltransferases - chemistry; DNA (Cytosine-5-)-Methyltransferases - metabolism; DNA Methylation; DNMT3A; Enzyme Activation; fluorescence; gel chromatography; Humans; Hydrogen-Ion Concentration; Kinetics; mechanism of action; methyltransferases; Models, Molecular; neoplasm cells; neoplasms; Oligomers; Processivity; Protein Conformation; Protein Multimerization; Structure-Activity Relationship; Oligomers; DNA methylation; pH; Processivity; DNMT3A; Cancer