Microvascular network alterations in retina of subjects with cerebral small vessel disease

• Published in: Neuroscience letters Vol. 577; pp. 95 - 100
• Main Authors: Hilal, Saima, Ong, Yi-Ting, Cheung, Carol Y., Tan, Chuen Seng, Venketasubramanian, Narayanaswamy, Niessen, Wiro J., Vrooman, Henri, Anuar, Ainur R., Chew, Merwyn, Chen, Christopher, Wong, Tien Yin, Ikram, Mohammad Kamran
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 08.08.2014
• Subjects: Aged; Biomarkers; Brain - pathology; Brain Infarction - epidemiology; Brain Infarction - pathology; Cerebral microbleeds; Cerebral small vessel disease; Cerebral Small Vessel Diseases - epidemiology; Cerebral Small Vessel Diseases - pathology; Chinese; Female; Humans; Magnetic Resonance Imaging; Male; Microvessels - pathology; Population based; Retinal microvascular changes; Retinal Vessels - pathology; Risk Factors; White Matter - pathology; Cerebral microbleeds; Chinese; Population based; Magnetic resonance imaging; Cerebral small vessel disease; Retinal microvascular changes

•Retinal microvascular network changes were linked previously to stroke and AD.•Sparser and more tortuous retinal vascular network was associated with CMB.•No significant association was found with lacunar infarcts and WML volume. Novel retinal imaging techniques have enabled the assessment of quant...