Selenocysteine-independent suppression of UGA codons in the archaeon Methanococcus maripaludis

• Published in: Biochimica et biophysica acta Vol. 1850; no. 11; pp. 2385 - 2392
• Main Authors: Seyhan, Deniz, Jehmlich, Nico, von Bergen, Martin, Fersch, Julia, Rother, Michael
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.11.2015
• Subjects: Amino Acid Sequence; bacteria; Codon; codons; cysteine; Formate dehydrogenase; Formate Dehydrogenases - physiology; formates; mass spectrometry; methane production; Methanococcus - genetics; Methanococcus maripaludis; Methanogenesis; Molecular Sequence Data; mutants; mutation; Protein Biosynthesis; protein synthesis; selenium; Selenocysteine; Selenocysteine - physiology; selenoproteins; Stop codon; Suppression; translation (genetics); tryptophan; Selenocysteine; Stop codon; Formate dehydrogenase; Methanococcus maripaludis; Suppression; Methanogenesis

Proteins containing selenocysteine (sec) are found in Bacteria, Eukarya, and Archaea. While selenium-dependence of methanogenesis from H2+CO2 in the archaeon Methanococcus maripaludis JJ is compensated by induction of a set of cysteine-containing homologs, growth on formate is abrogated in the absen...