Thioredoxin (Trx1) regulates CD4 membrane domain localization and is required for efficient CD4-dependent HIV-1 entry - Moolla, Naazneen; Killick, Mark; Papathanasopoulos, Maria; Capovilla, Alexio (Biochimica et biophysica acta, 2016)
Keywords: antibodies; antiretroviral properties; CCR5 receptor; CD4; CD4 Antigens - metabolism; Cell Line, Tumor; Cell Membrane - drug effects; Cell Membrane - metabolism; Cell Membrane - virology; centrifugation; confocal microscopy; disulfide bonds; Dithionitrobenzoic Acid - pharmacology; flow cytometry; glycoproteins; HeLa Cells; HIV-1; HIV-1 - pathogenicity; Human immunodeficiency virus 1; Humans; Lipid raft; major histocompatibility complex; Major Histocompatibility Complex - physiology; Membrane Microdomains - metabolism; Oxidation-Reduction - drug effects; pathogenicity; Receptors, CCR5 - metabolism; Redox; T-lymphocytes; T-Lymphocytes - drug effects; T-Lymphocytes - metabolism; T-Lymphocytes - virology; Thioredoxin; Thioredoxins - metabolism; Virus Internalization - drug effects; HIV-1; TFR; TCR; Lipid raft; DTNB; Grx1; Redox; MHC; Thioredoxin; Trx1; MBCD; CD4; APC; HIV; DRM