The cuproptosis-related signature associated with the tumor environment and prognosis of patients with glioma

• Published in: Frontiers in immunology Vol. 13; p. 998236
• Main Authors: Wang, Weichen, Lu, Zhichao, Wang, Maoyu, Liu, Zongheng, Wu, Bing, Yang, Chengkai, Huan, He, Gong, Peipei
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 30.08.2022
• Subjects: Apoptosis; Bexarotene; bioinformatics; Bortezomib; Brain Neoplasms - genetics; Brain Neoplasms - pathology; Class I Phosphatidylinositol 3-Kinases - genetics; clusters; Copper; cuproptosis; Cytarabine; DNA-Binding Proteins - genetics; ErbB Receptors - genetics; Gene Expression Regulation, Neoplastic; glioma; Glioma - genetics; Glioma - pathology; Humans; Immunology; Prognosis; RNA-Binding Proteins - genetics; signature; Tumor Microenvironment - genetics; glioma; cuproptosis; signature; clusters; bioinformatics

Copper ions are essential for cellular physiology. Cuproptosis is a novel method of copper-dependent cell death, and the cuproptosis-based signature for glioma remains less studied. Several glioma datasets with clinicopathological information were collected from TCGA, GEO and CGGA. Robust Multichip...