Quantitative proteomics and phosphoproteomics of Trypanosoma cruzi epimastigote cell cycle

• Published in: Biochimica et biophysica acta. Proteins and proteomics Vol. 1869; no. 5; p. 140619
• Main Authors: Santos Júnior, Agenor de Castro Moreira dos, Melo, Reynaldo Magalhães, Ferreira, Bianca Vasconcelos Gomes, Pontes, Arthur Henriques, Lima, Consuelo Medeiros Rodrigues de, Fontes, Wagner, Sousa, Marcelo Valle de, Lima, Beatriz Dolabela de, Ricart, Carlos André Ornelas
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2021
• Subjects: cell division; Chagas disease; chromatin; digestion; etiological agents; flow cytometry; fluorescence microscopy; hydroxyurea; Mitosis; phosphopeptides; Phosphoproteome; Proteome; proteomics; transcriptomics; Trypanosoma cruzi; Trypanosomatid; trypsin; Chagas disease; Proteome; Phosphoproteome; Trypanosomatid; Mitosis

The protozoan Trypanosoma cruzi is the causative agent of the neglected infectious illness Chagas disease. During its life cycle it differentiates into replicative and non-replicative life stages. So far, T. cruzi cell division has been investigated by transcriptomics but not by proteomics approache...