O-GlcNAc modification regulates MTA1 transcriptional activity during breast cancer cell genotoxic adaptation - Xie, Xueqin; Wu, Qiutong; Zhang, Keren; Liu, Yimin; Zhang, Nana; Chen, Qiushi; Wang, Lingyan; Li, Wenli; Zhang, Jianing; Liu, Yubo (Biochimica et biophysica acta. General subjects, 2021)
Keywords: Acetylglucosamine - chemistry; Acetylglucosamine - metabolism; angiogenesis; Apoptosis; Biomarkers, Tumor - genetics; Biomarkers, Tumor - metabolism; Breast cancer; breast neoplasms; Breast Neoplasms - genetics; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; breasts; Cell Proliferation; Chromatin - chemistry; Chromatin - genetics; Chromatin - metabolism; chromatin immunoprecipitation; DNA Damage; gain-of-function mutation; gene expression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; genes; Genotoxic adaptation; histones; Humans; mass spectrometry; MTA1; mutagens; N-Acetylglucosaminyltransferases - metabolism; neoplasm cells; nucleosomes; O-GlcNAc; Prognosis; Protein Processing, Post-Translational; proteomics; Repressor Proteins - chemistry; Repressor Proteins - genetics; Repressor Proteins - metabolism; serine; Survival Rate; Trans-Activators - chemistry; Trans-Activators - genetics; Trans-Activators - metabolism; transcription (genetics); transcriptomics; Tumor Cells, Cultured; Breast cancer; MTA1; O-GlcNAc; Genotoxic adaptation