Circular RNA expression profile of Alzheimer’s disease and its clinical significance as biomarkers for the disease risk and progression - Li, Yuanlong; Fan, Hua; Sun, Jun; Ni, Ming; Zhang, Lei; Chen, Ci; Hong, Xuejiao; Fang, Fengqin; Zhang, Wei; Ma, Peizhi (The international journal of biochemistry & cell biology, 2020)
Keywords: Aged; Alzheimer Disease - cerebrospinal fluid; Alzheimer Disease - genetics; Alzheimer’s disease; Amyloid beta-Peptides - cerebrospinal fluid; Amyloid beta-Peptides - genetics; Amyloid beta-Peptides - metabolism; biomarkers; Biomarkers - cerebrospinal fluid; cerebrospinal fluid; circular RNA; clinical significance; cytotoxicity; disease control; Disease Progression; Down-Regulation; expression profile; Female; Gene Ontology; Humans; Killer Cells, Natural - immunology; Logistic Models; Male; Microarray Analysis; microarray technology; MicroRNAs - cerebrospinal fluid; MicroRNAs - genetics; Middle Aged; mini-mental state examination score; natural killer cells; Nerve Growth Factors - cerebrospinal fluid; Nerve Growth Factors - genetics; Non-Neuronal Cholinergic System - genetics; Peptide Fragments - cerebrospinal fluid; Peptide Fragments - genetics; Peptide Fragments - metabolism; quantitative polymerase chain reaction; Real-Time Polymerase Chain Reaction; regression analysis; reverse transcription; reverse transcription quantitative polymerase chain reaction; risk; RNA, Circular - cerebrospinal fluid; RNA, Circular - genetics; ROC Curve; Signal Transduction - genetics; synapse; tau Proteins - cerebrospinal fluid; tau Proteins - genetics; tau Proteins - metabolism; Up-Regulation; miRNAs; AUC; SD; PNS; MMSE; circular RNA; SAMP8; CSF; KEGG; RT-qPCR; reverse transcription quantitative polymerase chain reaction; mini-mental state examination score; AD; Aβ42; Alzheimer’s disease; CI; ROC; GO; Ctrl; clinical significance; SAMR1; PCA; CircRNAs; FC; expression profile