Protein–RNA and protein–glycan recognitions in light of amino acid codes

• Published in: Biochimica et biophysica acta Vol. 1850; no. 9; pp. 1942 - 1952
• Main Authors: Nahalka, Jozef, Hrabarova, Eva, Talafova, Klaudia
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2015
• Subjects: adenine; alanine; Amino acid codes; Amino Acid Sequence; Amino Acids - genetics; Animals; aspartic acid; Cell developmental diseases; codons; Computational profiling; cytosine; diagnostic techniques; enzymes; Genetic Code; guanine; Humans; microRNA; Models, Molecular; Molecular Sequence Data; neoplasms; non-coding RNA; Polysaccharides - chemistry; Polysaccharides - metabolism; Protein engineering; Protein Structure, Tertiary; Proteins - chemistry; Proteins - metabolism; Protein–glycan interactome; Protein–RNA interactome; RNA - chemistry; RNA - metabolism; RNA-binding proteins; Sequence Analysis, Protein; uracil; valine; Protein engineering; Protein–RNA interactome; Protein–glycan interactome; Amino acid codes; Cell developmental diseases; Computational profiling

RNA-binding proteins, in cooperation with non-coding RNAs, play important roles in post-transcriptional regulation. Non-coding micro-RNAs control information flow from the genome to the glycome by interacting with glycan-synthesis enzymes. Glycan-binding proteins read the cell surface and cytoplasmi...