Omega-3 DHA- and EPA–dopamine conjugates induce PPARγ-dependent breast cancer cell death through autophagy and apoptosis - Rovito, Daniela; Giordano, Cinzia; Plastina, Pierluigi; Barone, Ines; De Amicis, Francesca; Mauro, Loredana; Rizza, Pietro; Lanzino, Marilena; Catalano, Stefania; Bonofiglio, Daniela; Andò, Sebastiano (Biochimica et biophysica acta, 2015)
Keywords: adjuvants; amines; antagonists; Apoptosis; Apoptosis - drug effects; Apoptosis Regulatory Proteins - genetics; Autophagy; Autophagy - drug effects; Beclin-1; bioactive properties; Breast cancer; breast neoplasms; Breast Neoplasms - drug therapy; Breast Neoplasms - pathology; chromatin; DNA damage; DNA fragmentation; docosahexaenoic acid; Docosahexaenoic Acids - pharmacology; Dopamine - pharmacology; eicosapentaenoic acid; Eicosapentaenoic Acid - pharmacology; epithelium; Female; Humans; immunoblotting; MCF-7 Cells; Membrane Proteins - genetics; neoplasm cells; Omega-3 polyunsaturated fatty acid conjugates; Peroxisome Proliferator-Activated Receptor gamma; PPAR gamma - physiology; precipitin tests; Promoter Regions, Genetic; RNA; viability; Beclin-1; Omega-3 polyunsaturated fatty acid conjugates; Breast cancer; Autophagy; Peroxisome Proliferator-Activated Receptor gamma; Apoptosis