Targeting biofilms and persisters of ESKAPE pathogens with P14KanS, a kanamycin peptide conjugate - Mohamed, Mohamed F.; Brezden, Anna; Mohammad, Haroon; Chmielewski, Jean; Seleem, Mohamed N. (Biochimica et biophysica acta. General subjects, 2017)
Keywords: Animals; Anti-Bacterial Agents - pharmacology; Anti-inflammatory; anti-inflammatory activity; antibacterial properties; antibiotic resistance; Antimicrobial peptides; bacteria; Bacterial Infections - drug therapy; Biofilm; Biofilms - drug effects; Caenorhabditis elegans; Caenorhabditis elegans - microbiology; Cell Line; Cell Membrane - microbiology; cell membranes; cytokines; ESKAPE; Humans; in vitro studies; Kanamycin; Kanamycin - pharmacology; mechanism of action; Microbial Sensitivity Tests - methods; pathogens; Peptides - pharmacology; Persisters; Biofilm; Kanamycin; ESKAPE; Anti-inflammatory; Antimicrobial peptides; Persisters