Geographic distribution of Trypanosoma cruzi genotypes detected in chronic infected people from Argentina. Association with climatic variables and clinical manifestations of Chagas disease

• Published in: Infection, genetics and evolution Vol. 78; p. 104128
• Main Authors: Bizai, María L., Romina, Peralta, Antonela, Simonetto, Olivera, Lorena V., Arias, Evelyn E., Josefina, Dalla Costa, Silvia, Manattini, Walter, Sione, Diana, Fabbro, Cristina, Diez
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.03.2020
• Subjects: Adult; Aged; Argentina; Argentina - epidemiology; Cardiomyopathies - etiology; cardiomyopathy; Chagas chronic cardiomyopathy; Chagas disease; Chagas Disease - epidemiology; Chagas Disease - etiology; Chronic Disease; Climate; evolution; Female; genetics; Genotype; Geographic distribution; geographical distribution; Humans; Latin America; Male; Middle Aged; people; Prevalence; probability; public health; temperature; Trypanosoma cruzi; Trypanosoma cruzi - genetics; Weather; Argentina; Latin America; Genotype; Climate; Geographic distribution; Chagas chronic cardiomyopathy; Trypanosoma cruzi

Chronic Chagas disease affects large number of people in Latin America where it remains one of the biggest public health problems. Trypanosoma cruzi is genetically divided into seven discrete typing units (DTUs), TcI-TcVI and Tcbat, and exhibits differential distribution across vectors, host and tra...