An Abbreviated Caries Clinical Trial Design Validated over 24 Months

• Published in: Journal of dental research Vol. 81; no. 9; pp. 637 - 640
• Main Authors: Chesters, R.K., Pitts, N.B., Matuliene, G., Kvedariene, A., Huntington, E., Bendinskaite, R., Balciuniene, I., Matheson, J.R., Nicholson, J.A., Gendvilyte, A., Sabalaite, R., Ramanauskiene, J., Savage, D., Mileriene, J.
• Format: Journal Article
• Language: English
• Published: United States SAGE Publications 01.09.2002; SAGE PUBLICATIONS, INC
• Subjects: Adolescent; Analysis of Variance; caries clinical trials; Cariostatic Agents - administration & dosage; Cariostatic Agents - therapeutic use; Child; clinical visual assessment; Dental Caries - diagnosis; Dental Caries - physiopathology; Dental Caries - prevention & control; Dental Caries Susceptibility; Dental Enamel - pathology; Dental Restoration, Permanent; Dentifrices - therapeutic use; Dentin - pathology; digital radiography; Disease Progression; DMF Index; Double-Blind Method; Dundee Selectable Threshold Method; Female; fiber optic transillumination; Fluorides - administration & dosage; Fluorides - therapeutic use; Follow-Up Studies; Humans; Male; Observer Variation; Radiography, Bitewing; Reproducibility of Results; Research Design; Statistics as Topic; Tooth Extraction; Tooth Remineralization; Transillumination; Treatment Outcome; digital radiography; fiber optic transillumination; clinical visual assessment; caries clinical trials; Dundee Selectable Threshold Method

Conventional caries trials last from 24 to 36 months. This study evaluated whether the previously established difference in efficacy between 1000- and 2500-ppm-fluoride dentifrices could be detected after 12 months. Caries was assessed by clinical visual assessment (CVA-simplified version of Dundee...