DEHP induces neutrophil extracellular traps formation and apoptosis in carp isolated from carp blood via promotion of ROS burst and autophagy

• Published in: Environmental pollution (1987) Vol. 262; p. 114295
• Main Authors: Yirong, Cao, Shengchen, Wang, Jiaxin, Sun, Shuting, Wang, Ziwei, Zhang
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.07.2020
• Subjects: Apoptosis; Autophagy; carp; Di (2-ethylhexyl) phthalate; DNA; dynein ATPase; endocrine-disrupting chemicals; humans; immunotoxicity; Neutrophil extracellular traps; neutrophils; phthalates; quantitative analysis; reactive oxygen species; ROS production; Di (2-ethylhexyl) phthalate; Autophagy; Neutrophil extracellular traps; ROS production; Apoptosis

Di (2-ethylhexyl) phthalate (DEHP), a widely spreading environmental endocrine disruptor, has been confirmed to adversely affect the development of animals and humans. The formation of neutrophil extracellular traps (NETs) termed NETosis, is a recently identified antimicrobial mechanism for neutroph...