Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease - Vassilakopoulou, Vyronia; Calver, Brian L.; Thanassoulas, Angelos; Beck, Konrad; Hu, Handan; Buntwal, Luke; Smith, Adrian; Theodoridou, Maria; Kashir, Junaid; Blayney, Lynda; Livaniou, Evangelia; Nounesis, George; et al. (Biochimica et biophysica acta, 2015)
Keywords: Animals; Calcium; Calcium - metabolism; calcium channels; Calmodulin; Calmodulin - genetics; Cardiac disease; heart failure; in vitro fertilization; Long QT Syndrome - etiology; missense mutation; muscle contraction; mutants; Mutation; myocardium; patients; Polymorphic Catecholaminergic Ventricular Tachycardia; Ryanodine receptor; Ryanodine Receptor Calcium Release Channel - physiology; RyR2 calcium release channel; sarcoplasmic reticulum; Swine; tachycardia; Tachycardia, Ventricular - etiology; RyR2; CD; ECC; Calcium; Cardiac disease; LQTS; Ryanodine receptor; CaM; CPVT; Ca2; IVF; RyR2 calcium release channel; Calmodulin; SR