Peptidoglycan Enhances IL-6 Production in Human Synovial Fibroblasts via TLR2 Receptor, Focal Adhesion Kinase, Akt, and AP-1- Dependent Pathway - Chiu, Yung-Cheng; Lin, Ching-Yuang; Chen, Chao-Ping; Huang, Kui-Chou; Tong, Kwok-Man; Tzeng, Chung-Yuh; Lee, Tu-Sheng; Hsu, Horng-Chaung; Tang, Chih-Hsin (The Journal of immunology (1950), 2009)
Keywords: Adjuvants, Immunologic - pharmacology; Adjuvants, Immunologic - physiology; Adjuvants, Immunologic - secretion; Arthritis, Rheumatoid - immunology; Arthritis, Rheumatoid - metabolism; Arthritis, Rheumatoid - pathology; Cells, Cultured; Fibroblasts - immunology; Fibroblasts - pathology; Fibroblasts - secretion; Focal Adhesion Kinase 1 - physiology; Gene Expression Regulation - immunology; Humans; Inflammation Mediators - metabolism; Inflammation Mediators - physiology; Interleukin-6 - biosynthesis; Interleukin-6 - genetics; Interleukin-6 - secretion; Peptidoglycan - pharmacology; Phosphatidylinositol 3-Kinases - metabolism; Phosphatidylinositol 3-Kinases - physiology; Proto-Oncogene Proteins c-akt - physiology; Signal Transduction - immunology; Synovial Membrane - enzymology; Synovial Membrane - pathology; Synovial Membrane - secretion; Toll-Like Receptor 2 - physiology; Transcription Factor AP-1 - physiology