Application of advanced X-ray methods in life sciences

• Published in: Biochimica et biophysica acta. General subjects Vol. 1861; no. 1; pp. 3671 - 3685
• Main Authors: Sayers, Zehra, Avşar, Bihter, Cholak, Ersoy, Karmous, Ines
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2017
• Subjects: absorption; Animals; Biological Science Disciplines - methods; crystallography; Crystallography, X-Ray; fluorescence emission spectroscopy; image analysis; Macromolecular crystallography (MX); Macromolecular Substances - chemistry; proteins; Scattering, Small Angle; Small angle solution scattering (SAXS); Spectrum Analysis; structure-activity relationships; Synchrotron radiation; tissues; X-radiation; X-ray absorbance and fluorescence spectroscopy (XAFS); X-ray imaging; X-Rays; X-ray absorbance and fluorescence spectroscopy (XAFS); Small angle solution scattering (SAXS); Macromolecular crystallography (MX); Synchrotron radiation; X-ray imaging

Synchrotron radiation (SR) sources provide diverse X-ray methods for the investigation of structure–function relationships in biological macromolecules. Recent developments in SR sources and in the X-ray tools they offer for life sciences are reviewed. Specifically, advances in macromolecular crysta...