Fluorine-18: Radiochemistry and Target-Specific PET Molecular Probes Design

• Published in: Frontiers in chemistry Vol. 10; p. 884517
• Main Authors: Wang, Yunze, Lin, Qingyu, Shi, Hongcheng, Cheng, Dengfeng
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 29.06.2022
• Subjects: 18 F-radiolabeling; Chemistry; fluorination; fluoroalkylation; PET imaging; PET radiotracers; fluorination; fluoroalkylation; 18 F-radiolabeling; PET imaging; PET radiotracers

The positron emission tomography (PET) molecular imaging technology has gained universal value as a critical tool for assessing biological and biochemical processes in living subjects. The favorable chemical, physical, and nuclear characteristics of fluorine-18 (97% β + decay, 109.8 min half-life, 6...