Inhibition of TNF-α, and NF-κB and JNK pathways accounts for the prophylactic action of the natural phenolic, allylpyrocatechol against indomethacin gastropathy - Yadav, Sudhir K.; Adhikary, Biplab; Bandyopadhyay, Sandip K.; Chattopadhyay, Subrata (Biochimica et biophysica acta, 2013)
Keywords: adhesion; adverse effects; Angiogenesis; Animals; Anti-Inflammatory Agents, Non-Steroidal - adverse effects; Anti-Inflammatory Agents, Non-Steroidal - pharmacology; anti-ulcer activity; Anti-Ulcer Agents - pharmacology; antioxidant activity; antioxidants; Catechols - chemistry; Catechols - pharmacology; Disease Models, Animal; enzyme-linked immunosorbent assay; Gastric ulcer; growth factors; histology; Indomethacin; Indomethacin - adverse effects; Indomethacin - pharmacology; Inflammatory modulator; Male; MAP Kinase Signaling System - drug effects; messenger RNA; Mice; Misoprostol - pharmacology; mitogen-activated protein kinase; nonsteroidal anti-inflammatory agents; NSAID; Omeprazole - pharmacology; oxidative stress; Oxidative Stress - drug effects; pharmacokinetics; Piper betle - chemistry; prostaglandins; receptors; Stomach Ulcer - chemically induced; Stomach Ulcer - drug therapy; Stomach Ulcer - metabolism; Stomach Ulcer - pathology; transcription factor NF-kappa B; tumor necrosis factor-alpha; Tumor Necrosis Factor-alpha - metabolism; Angiogenesis; Inflammatory modulator; Indomethacin; Gastric ulcer; NSAID