Characterizing the mode of action of extracellular Connexin43 channel blocking mimetic peptides in an in vitro ischemia injury model - Kim, Yeri; Griffin, Jarred M.; Harris, Paul W.R.; Chan, Sin Hang Crystal; Nicholson, Louise F.B.; Brimble, Margaret A.; O'Carroll, Simon J.; Green, Colin R. (Biochimica et biophysica acta. General subjects, 2017)
Keywords: adenosine triphosphate; Adenosine Triphosphate - metabolism; amino acid substitution; Cell Line; central nervous system; Central Nervous System Diseases - drug therapy; Central Nervous System Diseases - metabolism; Cerebrum - drug effects; Cerebrum - metabolism; chronic diseases; Connexin 43 - metabolism; Connexin43; endothelial cells; Endothelial Cells - drug effects; Endothelial Cells - metabolism; Gap junctions; Gap Junctions - drug effects; Gap Junctions - metabolism; Hemichannel; Humans; Ion Channels - metabolism; Ischemia; Ischemia - drug therapy; Ischemia - metabolism; mechanism of action; Peptide5; peptides; Peptides - pharmacology; Peptidomimetics; permeability; Reperfusion Injury - drug therapy; Reperfusion Injury - metabolism; Retinal Diseases - drug therapy; Retinal Diseases - metabolism; Peptide5; Ischemia; Peptidomimetics; Gap junctions; CNS; Connexin43; Hemichannel; ATP; hCMVEC