H2S-induced S-sulfhydration of pyruvate carboxylase contributes to gluconeogenesis in liver cells - Ju, YoungJun; Untereiner, Ashley; Wu, Lingyun; Yang, Guangdong (Biochimica et biophysica acta, 2015)
Keywords: Animals; biogenesis; biotin; CSE; cystathionine gamma-lyase; cysteine; Cysteine - metabolism; diabetes; Diet, High-Fat; Gluconeogenesis; glucose; Glucose - biosynthesis; H2S; HEK293 Cells; Hep G2 Cells; hepatocytes; high fat diet; human cell lines; Humans; hydrogen sulfide; Hydrogen Sulfide - pharmacology; insulin resistance; lipoproteins; liver; Liver - metabolism; Male; messenger RNA; Mice; mitochondria; mutation; pyruvate carboxylase; Pyruvate Carboxylase - metabolism; quantitative polymerase chain reaction; S-sulfhydration; Western blotting; PBS; KO; DTT; HFD; H2S; S-sulfhydration; NAD; DMEM; NADH; PC; CSE; 3-MPST; MMTS; WT; Gluconeogenesis; HS