An in vitro investigation of the inhibitory mechanism of β-galactosidase by cinnamaldehyde alone and in combination with carvacrol and thymol - Wang, Lang-Hong; Wang, Man-Sheng; Zeng, Xin-An; Gong, De-Ming; Huang, Yan-Bo (Biochimica et biophysica acta. General subjects, 2017)
Keywords: Acrolein - analogs & derivatives; Acrolein - chemistry; Acrolein - pharmacology; active sites; antibiotics; atomic force microscopy; bark; beta-galactosidase; beta-Galactosidase - antagonists & inhibitors; beta-Galactosidase - metabolism; Binding Sites; bioactive properties; biochemical pathways; carvacrol; Cinnamaldehyde; cinnamon; Circular Dichroism; circular dichroism spectroscopy; Cluster Analysis; Competitive inhibition; Enzyme Inhibitors - chemistry; Enzyme Inhibitors - pharmacology; fluorescence; Hydrogen-Ion Concentration; ingredients; Kinetics; leaves; mechanism of action; Microscopy, Atomic Force; Molecular Docking Simulation; Molecular modeling; molecular models; Monoterpenes - chemistry; Monoterpenes - pharmacology; nucleic acids; proteins; Spectrometry, Fluorescence; synergism; Synergistic effect; thymol; Thymol - chemistry; Thymol - pharmacology; tryptophan; tyrosine; β-Galactosidase; Cinnamaldehyde; Synergistic effect; Competitive inhibition; Molecular modeling; β-Galactosidase