Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin - Kim, Tae Hyung; Shin, Yu Jin; Won, A. Jin; Lee, Byung Mu; Choi, Wahn Soo; Jung, Jee H.; Chung, Hae Young; Kim, Hyung Sik (Biochimica et biophysica acta, 2014)
Keywords: ABC transporters; Animals; antineoplastic activity; Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics; Antineoplastic Combined Chemotherapy Protocols - pharmacology; Apoptosis - drug effects; ATP Binding Cassette Transporter, Sub-Family B; ATP-Binding Cassette, Sub-Family B, Member 1 - genetics; ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism; Blotting, Western; Breast cancer; breast neoplasms; Breast Neoplasms - drug therapy; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; Cell Proliferation - drug effects; cytotoxicity; Doxorubicin; Doxorubicin - administration & dosage; Drug Resistance, Multiple - drug effects; Drug Resistance, Neoplasm - drug effects; Drug Synergism; Drug-resistant; Female; genes; Humans; in vivo studies; Mice; Mice, Inbred BALB C; Multidrug Resistance-Associated Proteins - genetics; Multidrug Resistance-Associated Proteins - metabolism; multiple drug resistance; neoplasm cells; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - genetics; Stilbenes - administration & dosage; synergism; Tissue Distribution; Tumor Cells, Cultured; P-gp; Drug-resistant; DMSO; MRP; Breast cancer; Dox; Doxorubicin; DMEM; TUNEL; RSV; RT-PCR; Resveratrol; MCF-7/adr; MDR; ABC transporter; Multi-drug resistance; Terminal deoxynuclotidyl transferase dUTP nick end labeling; Dimethylsulfoxide; Dulbecco's Modified Eagle Medium; P-glycoprotein; Multi-drug resistance associated protein; Doxorubicin-resistant MCF-7; ATP-binding cassette transporter; Reverse transcription polymerase chain reaction